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Unconventional ways to live and die: cell death and survival in development, homeostasis, and disease

Poly(ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks

In addition, another study found that PPAR can also play a protective role in the pathological process of OA by inhibiting the activation of the MAPK and NF-B signaling pathways, reducing the release of inflammatory factors, inhibiting chondrocyte apoptosis, and reducing the local inflammatory response 37

Finally, GSH availability negatively regulates SLC25A39 protein abundance, coupling redox homeostasis to mitochondrial GSH import in mammalian cells

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