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Description

5-Fluorouracil enhances the antitumor activity of the glutaminase inhibitor CB-839 against PIK3CA-mutant colorectal cancers

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13 Following repeated administration of 2 g of Lcarnitine orally every 12 h for 4 days in 3 different formulations (chewable tablet, oral solution and tablet), the time to maximum concentration was 3.13.4 h, with a peak plasma concentration of 53.854.2 mol/L and trough plasma concentration of 53.854.5 mol/L

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