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The different types of disease-associated melanoses listed below are highly correlated with oral/perioral pigmentation and are of prime concern in a differential diagnosis: Addisons disease Peutz-Jeghers syndrome Chronic lichen planus Laugier-Hunziker syndrome Neurofibromatosis McCune-Albright syndrome Kaposi sarcoma The prognosis for oral melanotic macules is excellent, and they are followed and monitored after diagnosis through documentation and photographs/images

Media reports at the time speculated that Williams had resumed drinking alcohol, but the statement from his wife appears to dispute those reports

Most common adverse effects are gastrointestinal, but some symptoms can overlap with serious medication warnings

The Reddit user claims he injects himself with Melanotan-II 'for the skin coloring'