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The children that participated in the study had appropriate suppression of insulin secretion in response to hypoglycemia and had a normal fasting tolerance, arguing against an underlying disorder of insulin secretion (39)

Discontinuation and Reinitiation of Dual-Labeled GLP-1 Receptor Agonists Among US Adults With Overweight or Obesity

The same study highlighted higher baseline abundance of Bacteroides dorei in responders, suggesting that certain Bacteroides species may be associated with improved metabolic flexibility or incretin responsiveness

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These factors must be taken into account when assessing the balance of benefits and risks for using GLP-1 medications, he said