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Animals were then pair-fed the control or the ethanol liquid diet for 8 weeks (pair-feeding was based on ethanol diet consumption) in the following groups: pair-fed control, EtOH-fed, pair-fed EtOH + ALC, pair-fed EtOH + CoQ10, and pair-fed ALC alone (eight mice/group, or three mice/basal control of ALC or CoQ10)

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Step four is following dosing instructions exactly, including titration guidance

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The disease recurrence rate among the 19 patients with known data was 36.84% (7/19)