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[DOI] [PubMed] [Google Scholar] 24.Fyfe J.C., Madsen M., Hjrup P., Christensen E.I., Tanner S.M., de la Chapelle A., He Q., Moestrup S.K

Because apparent clearance was 3441% lower in the youngest/lightest children, a weight-based (mg/kg) regimen was selected to achieve comparable systemic exposure across all ages and weights and for getting the target (about 4073% across bands) compared to placebo