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In the case of GLP-1 RAs like Wegovy and Mounjaro, theres technically an autoinjector shortage, but its impacting the availability of GLP-1 RAs nonetheless

Rapid cessation may trigger appetite rebound, weight regain, and metabolic dysregulation

10.1371/journal.pone.0311152 94 XuZ.ZhangM.WangY.ChenR.XuS.SunX.et al (2022)

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Domingues M, Casaril AM, Birmann PT, Bampi SR, Lourenco DA, Vieira BM, Dapper LH, Lenardao EJ, Sonego M, Collares T, Seixas FK, Bruning CA, Savegnago L (2019) Effects of a selanylimidazopyridine on the acute restraint stress-induced depressive- and anxiety-like behaviors and biological changes in mice