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Mechanistically, the thioredoxin interacting protein (TXNIP) serves as a link between cellular redox state and NLRP3 activation

This is well-documented in the broader growth hormone literature

While GHRPs primarily stimulate the ghrelin receptor, Sermorelin acts through the GHRH receptor, making it one of the more physiologically targeted approaches to supporting endogenous growth hormone release

One of the conclusions of that study demonstrates that glutathione in fact boosts mitochondria performance

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