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Serious concerns with unregulated/high-dose use: infections from non-sterile settings, kidney or liver stress at very high doses over time, and (rarely) thyroid disruption

No muscle loss: detected by dual energy X-ray absorptiometry (DXA), the high-dose form maintained stable lean body mass, while the placebo form showed a slight decrease

These may include: Pancreatitis (inflammation of the pancreas) Gallbladder problems Increased risk of thyroid tumors (seen in animal studies) Changes in kidney function Interactions with other medications Can You Stop GLP-1s at Any Time