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Vitamin B6 Supports: Neurotransmitter production and nerve signal regulation Caution: Excessive doses may actually worsen sciatic nerve pain so doses should be monitored carefully Found in: Leaf vegetables, whole grains, bananas, nuts 3

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SIRT1 function is also modulated through protein-protein interactions: DBC1 inhibits SIRT1 activity via complex formation, 30,49 whereas AROS and SENP1 interact with SIRT1 to enhance its activity, expanding the spectrum of functional regulation

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