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For instance, the metabolite hydrogen sulfide (H 2 S), which was produced by Desulfovibrio has been shown to impair GLP-1 expression, thereby disrupting host glucose metabolism ( Taken together, these findings demonstrate that gut microbiota and their metabolites exert dual and context-dependent effects on GLP-1 secretion and signaling

For this reason, its therapeutic potential concerns a series of diseases that link oxidative stress to its etiology and progression [3,4]