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2020 Feb 9;9(2):474

It has been observed that flavonoids and several alkaloids can act as antioxidants, anticancer agents, antibacterial agents, anti-inflammatory agents, and interesting applicants for pharmaceutical and medical applications (70, 71)

This hypothesized systemic dissemination of inflammation constitutes the mechanistically plausible pathophysiological bridge between testicular dysfunction and penile ED, a mechanism that has long been underrecognized in traditional research focusing solely on local testicular changes (204)

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