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Am J Psychiatry 160:221236 Alquier T, Christian-Hinman CA, Alfonso J, Frgeman NJ (2021) From benzodiazepines to fatty acids and beyond: revisiting the role of ACBP/DBI

While CJC-1295/Ipamorelin offers a synergistic approach with intermittent and sustained GH release, potentially benefiting muscle growth and fat loss, Tesamorelin is primarily prescribed for HIV-related lipodystrophy and has a more targeted effect on reducing visceral fat

Stress Suppresses GLP-1 (The Cortisol Cravings Loop) Cortisol decreases natural GLP-1 by: reducing SCFA-producing bacteria increasing inflammation flattening the circadian rhythm damaging mucosal integrity destabilizing serotonin and appetite signals This leads to: Stress cortisol low GLP-1 cravings overeating belly fat Reference Stress & Eating Behavior (Annual Review of Psychology, 2019) 7

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doi: 10.14814/phy2.14651 27 BiswasSCButeauJGreeneLA