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While designing treatment strategies aimed at improving stroke recovery, greater attention should be paid to non-neuronal cells which are able to produce substantial amounts of BDNF after ischemic stroke

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Intranasal administration is particularly studied for its ability to bypass the blood-brain barrier via retrograde axonal transport

For example, choosing 2.5mg/mL concentration requires 2mL bacteriostatic water and delivers 250mcg per 0.1mL (10 units on a U-100 syringe)