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However, it should be noted that NLRP3 deficiency causes undesirable infection in mice [10], and MCC950 was not recommended in a phase II clinical trial for rheumatoid arthritis due to its liver toxicity [40]

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doi: 10.3390/nu12051389 Acetyl-L-carnitine-induced up-regulation of heat shock proteins protects cortical neurons against amyloid-beta peptide 1-42-mediated oxidative stress and neurotoxicity: implications for Alzheimers disease

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