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This includes options like intrauterine devices (IUDs), injections, implants, rings, and patches

This poses another limitation, casting doubt on the generalizability of our findings

5 These guidelines align with the American Diabetes Association (ADA) standards of care which also provide strong recommendations based on robust clinical trial data supporting the cardiovascular benefits of GLP-1 RAs, particularly in patients with established cardiovascular disease and chronic kidney disease (CKD)

It includes GLP-1 receptor activity, but unlike semaglutide, it is a triple agonist, also targeting GIP and glucagon receptors for broader metabolic effects

- Reduction of insulin secretion (calcium antagonists, diazoxide, somatostatin analogues, IL-1 receptor antagonist)