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More recent research has confirmed that low plasma PLP status is associated with CAD

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Studies in Caenorhabditis elegans have shown that the reciprocal regulation of CDF-2 (a ZnT-like importer) and ZIPT-2.3 (a ZIP-like exporter) on lysosome-related organelles mediates zinc storage during excess and release during deficiency, demonstrating a conserved directional flow of zinc 102