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Artemisinin can induce ferroptosis in prostate cancer cell DU145, but no similar effect was observed in PC3 and LNCaP cell lines [45]

The results in arms in A and B were similar, with a later onset of action in arm A, which is expected for epigenetic regulators [49]

Its main active ingredient, polysaccharides (GLPs), treats complications including nephropathy, liver injury, cardiomyopathy, neuropathy, retinopathy, and erectile dysfunction due to diabetes through multi-target pathways, including improving glucose and lipid metabolism (Jones, 2016), regulating oxidative stress (Yamada et al., 2020), inhibiting cell apoptosis (Xia et al., 2021), repairing islet cells (Li et al., 2017), alleviating inflammatory responses (Wang L

It has a long half-life, which allows for sustained GH release and steady increases in circulating insulin-like growth factor-1 (IGF-1) levels, both of which support cellular repair and metabolism

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