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1, both groups exhibited decreases in HbA1c and body weight, but a significant reduction in HbA1c was observed only in the 10 mg group

BPC-157 and TB-500 appear relatively well-tolerated in reported use, though formal safety data remains limited

Collectively, these data show that the ability of GIPR antagonism to enhance GLP-1-induced weight loss is not mediated by GIPR signal inhibition in peripherin-expressing peripheral neurons

It allows the peptide to work systemically with minimal risk

At the same time, a 2026 Aon analysis found that sustained GLP1 use for employees with Type 2 diabetes was associated with 6% lower medical cost growth after 30 months, highlighting both the budget impact and the potential longterm savings