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They can slow gastric emptying, potentially affecting absorption of oral meds, but clinically this is rarely significant
Weight loss and diabetes management can sometimes take a toll on your mental well-being
Additional risk factors include pre-existing gastroparesis, diabetes-related autonomic neuropathy, Parkinson disease, connective tissue disorders affecting gastrointestinal motility, and concurrent use of medications known to slow gastric emptying
In a yearlong Phase 3 trial, the highest dose of Lilys pill, orforglipron, lowered a measure of blood sugar called A1C by 1.9 percentage points, while the highest dose of Novos drug, marketed as Rybelsus, lowered A1C by 1.5 percentage points, when analyzing all patients regardless of discontinuations
10.1016/s0741-8329(03)00104-6 11 ChenK.GuoN.ZhangR.WeiC.GuoR
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