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10.1007/s00586-011-1975-3

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Functional peptides were only verified in non-human primates, whereas in all other mammals the truncated -defensin precursors have additional premature stop codons and are pseudogenes [127, 128]

The MHRA ( Medicines and Healthcare products Regulatory Agency ) has two main application procedures: Simple Reclassification : This is a straightforward and quick procedure based on an analogous product (a medicinal product already on the UK market with the same active ingredient, route of administration, use, and a similar or higher strength/dosage)