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doi:10.1002/ddr.21345 Anderson S, Panka J, Rakobitsch R, Tyre K, Pulliam K

Consistent with this finding, no improvement in glucose tolerance was observed during an intraperitoneal glucose tolerance test in C57BL6 mice that were administered a subcutaneous dose of PF-06882961 (10 mg/kg) (Fig

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These results indicate that the inhibition of mTOR is able to reduce immunosenescence which might explain the lifespan extension of mice with rapamycin therapy [18, 19]