the trade-off is convenience versus control
doi:10.1023/A:1024931311845 PMID:12910291 Korkushko OV, Khavinson VKh, Shatilo VB, Antonyk-Sheglova IA
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As can be seen from Figures 4 , the samples of NC, FI and GSH groups are all in the 95% confidence interval, and can be spatially separated uniformly without overlap, indicating that there are significant differences in metabolites between the two groups, and that they are able to be analyzed in the next step
Indeed, in a model of graft-versus-host disease (GVHD), T-cell-depleted bone marrow transplants fed with TMAO-rich diet exhibited a significant increase in the frequency of F4/80 + CD11b + CD16/32 + inflammatory macrophages relative to the F4/80 + CD11b + whole population, worsening disease severity, and increasing mortality (80)