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DOI: Coukos JA, Howard LA, Weinberg JM, et al

Semaglutide might indirectly improve CV and kidney-related outcomes, but the exact mechanisms by which GLP-1RAs exert beneficial effects on CV and kidney parameters are not yet elucidated, in contrast to the well-established intrarenal tubulo-glomerular feedback mechanism of SGLT2is [13]

The results are better appreciated in primary lipolysis

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