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Even if tiny amounts of semaglutide did reach the infant through milk, the oral bioavailability of semaglutide in adults maxes out at approximately 1 percent

Meal planning and timing tailored to individual schedules can help overcome common barriers and optimise the effectiveness of GLP-1 medications

Suitable candidates include: Patients with type 2 diabetes and a BMI of 35 kg/m or higher (or 32.5 kg/m or higher for people of South Asian or other minority ethnic backgrounds), or where weight loss would benefit other significant obesity-related comorbidities Those with type 2 diabetes who have not achieved target HbA1c levels with metformin and other oral medications People for whom weight loss would benefit other obesity-related comorbidities or where weight-neutral treatment options are preferred Individuals with occupational implications where insulin therapy would be problematic Importantly, NICE recommends continuing GLP-1 receptor agonist treatment only if there is a beneficial metabolic response: after 6 months, treatment should continue only if HbA1c has decreased by at least 11 mmol/mol (1.0%) and weight has decreased by at least 3% from initial body weight

Or what if genetic variations cause your enzymes to work slowly

Within 1-2 hours , your body starts absorbing the medication