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Research continues into additional potential benefits and applications

Limited access to GLP-1s in low-income and high-obesity regions threatens to widen existing health inequities, particularly in rates of diabetes, cardiovascular disease, and mobility-related conditions

Slower rates suggest potential underdosing, assuming dietary compliance remains strong

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This supports a multifactorial model in which semaglutide may amplify ischemic susceptibility in predisposed individuals, such as those with small BMO, ODD or otherwise crowded optic nerve head, rather than acting as a direct neurotoxic agent