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Biologic therapies effectively target specific inflammatory mediators, but do not directly address metabolic dysfunction or oxidative stress, both of which contribute to HS severity

Semaglutide, a GLP-1 receptor agonist found in Ozempic, helps control blood sugar by promoting the synthesis of insulin, decreasing the livers release of glucose, and delaying the intestinal absorption of sugar

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Similarly, Lai and colleagues utilized self-assembly technology to combine ursolic acid nanoparticles with carbon dots [62]