The protocol works when executed correctly
Rubino D., Abrahamsson N., Davies M., et al., Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial, Journal of the American Medical Association 325 (2021): 14141425
No pancreatic safety concern following glucagon-like peptide-1 receptor agonist therapies: a pooled analysis of cardiovascular outcome trials
A more complete investigation of relevant human GSTs is required for understanding the scope of JS-K biotransformation and the consequent cellular effects in neoplastic as well as normal tissues
Esto no significa que el frmaco no funcione, sino que, como cualquier tratamiento para una condicin crnica, la retirada debe ser planificada, gradual y acompaada de refuerzo de los pilares que sostienen el peso saludable: alimentacin adecuada, aporte micronutricional, actividad fsica, preservacin de masa muscular, gestin del estrs, control de la inflamacin, cuidado de la microbiota y optimizacin del sueo