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PMID: 8882911 Edwards R, Peet M, Shay J, Horrobin D (1998) Omega-3 polyunsaturated fatty acid levels in the diet and in red blood cell membranes of depressed patients

PMID: 9005976

And it's why every serum on your shelf has stopped working the way it used to

The ability of glutamate to improve intestinal barrier function is also demonstrated in a study using adult human IEC lines, where glutamate addition significantly reduced phorbol-induced hyperpermeability (133)

What that longer-term care looks like: Medication-assisted treatment (MAT): FDA-approved medications including buprenorphine (Suboxone) and naltrexone (Vivitrol) reduce cravings and can help prevent return to use