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This combination works primarily in the brain, reducing cravings and the pleasure response to food rather than creating physical feelings of fullness

These results highlight how difficult it is for adolescents to keep weight off once they lose it. Those taking exenatide had an increase of 8 bpm in heart rate from randomization to 1 year compared with a 1 bpm increase for placebo ( P = .03)

Biomedicines 2021, 9(4)

Bonner C, Kerr-Conte J, Gmyr V, et al

Researchers believe the compounds effectiveness comes from its triple-receptor activity: GLP-1 Activation GLP-1 signaling is associated with appetite regulation and improved glucose control