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These metabolic changes were supported by alterations in the gene expression of choline metabolism-related enzymes, such as choline dehydrogenase ( Chdh ), betaine-homocysteine methyltransferase ( Bhmt ), and DMG dehydrogenase ( Dmgdh ), and glycerophosphocholine phosphodiesterase 1 ( Gpcpd1 )

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Intra cranial hypertension appears inducing coma, cerebral engagement and death of the patient

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In response to bouts of exercise, circulating levels of reduced glutathione are found to decrease while levels of oxidized glutathione increase