glutathione supplement uses Reduced with Milk Thistle - 500 mg per Serving Pure L Glutathione with Alpha Lipoic Acid & Milk Thistle Silymarin Glutathione 1000mg x 240 Tablets

This allows the Glutathione to be absorbed through the rectal mucosa directly into the bloodstream, bypassing the digestive system and liver metabolism, which can degrade the Glutathione before it can exert its effects

Published literature reports doses of 12 mg/kg for in vivo research

It is a tripeptide made from three amino acids: cysteine, glutamate, and glycine

Hibbert JM, Creary MS, Gee BE, et al

However, growing evidence indicates that alternative metabolic routes such as malic enzyme 1 (ME1), isocitrate dehydrogenases (IDH1 and IDH2), and the folate cycle also significantly contribute to NADPH production, particularly under stress conditions or during metabolic reprogramming [43]