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298 In addition, IVIGs seem to increase the incidence of several serious adverse events in ARDS patients, such as septic shock, acute kidney injury, and bacterial pneumonia

doi: 10.1016/s0022-5347(17)39746-x

The positively charged lysine side chain at physiological pH may play a role in interactions with negatively charged cellular surfaces, with extracellular matrix components, and with DNA, and may contribute to the cellular uptake and tissue distribution properties of the complex

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