Continuous activation of c-Met receptors without recovery periods may lead to receptor internalization and reduced surface expressiona protective mechanism cells employ when signaling pathways are overstimulated
In addition, the clearance of apoptotic trophoblasts causes the IL-10 production, and suppression of inflammatory cytokines by macrophages, suggesting that efferocytosis plays an important role in maternal-tolerance [23], while in the post-lactation apoptotic cell clearance at the mammary gland drives tissue remodeling [24]
doi: 10.1097/JU.0000000000003492 188 MerrielSWDPocockLGilbertECreavinSWalterFMSpencerAet al
3.2 Stem cell therapy Another method is stem cell therapy, which uses a wide variety of techniques, often in conjunction with the aforementioned biomaterials, to improve the efficacy of the biomaterial construct or to tackle multiple concerns simultaneously
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