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Genetically encoded sensors for pyridine nucleotides were relative latecomers, however, significant progress has been made over the past decade in developing sensors for NADH [9], NAD + [10, 11], NADH/NAD + [1214], NADPH [15], and NADP + [16, 17]

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By increasing brain creatine levels, creatine may help protect the brain against metabolic stress

This makes it a significant molecule in combating the signs of ageing and maintaining overall cellular health

in the writing of the manuscript, or in the decision to publish the results