It is important to distinguish between classical treatments, which are well-established and commonly used in clinical practice such as L-DOPA, catechol-O-methyltransferase inhibitors, monoamine oxidase inhibitors, dopamine agonists, amantadine, and deep brain stimulation, novel treatments, which are still in the experimental or research stage, show promise as potential future therapeutic approaches such as stem cell therapy, graft assisted neural reconstruction, novel targets for disease modification, neurotrophic factors, and cannabinoids
When to increase dose Consider increasing if: Minimal response after 4-6 weeks at current dose No side effects at current dose Current dose below the higher end of recommended range Goals not being met with conservative approach Increase gradually, typically by 25-50% at a time
Materials and methods Fungal inocula Serendipita indica was provided by Prof
Genomics 15, 493501 (2005)
Daily use of sunscreen SPF 50 protects fresh cells from UV damage, otherwise your progress will be reversed
