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How long will it take to improve

Kayser et al

Hard training depletes glutathione, which increases oxidative stress, slows recovery, and weakens immune function

While ARA-290 has shown no tumor-promoting effects in studies, its tissue-protective properties theoretically could affect cancer cells

Of importance, GLS inhibition and IDH1 mutations are synthetically lethal under oxidative stress, and GLS inhibition with CB-839 has been shown to selectively radiosensitize the IDH1 mutated xenograft GBM tumors [159]