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The ones waiting for the trend to become undeniable are ceding that window, and Circanas analysis adds a further layer of urgency: the categories with the steepest GLP-1 spending declines are often the same categories with the most bloated SKU counts, the result of years of incremental product extensions that made sense when volume was growing but become expensive to maintain as demand contracts

April 2021: Anaphylaxis and other immune reactions are reported with the use of Ozempic and added to the drugs label

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