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Seek urgent medical attention (call NHS 111 or 999 in an emergency) if you develop severe abdominal pain especially pain that radiates to the back (which may indicate pancreatitis) or right upper quadrant pain with fever or jaundice (which may indicate gallbladder disease)

These results demonstrate that the low molecular weight bioactive peptides contained in CPNS, such as Gly-Pro and Pro-Hyp, exert positive effects on skin hydration, elasticity, desquamation, and wrinkling

Koffert J, Honka H, Teuho J, Kauhanen S, Hurme S, Parkkola R, Oikonen V, Mari A, Lindqvist A, Wierup N, et al

Rather than binding directly to the enzyme active site, copper ions interfere with the enzymes function at concentrations achievable through topical or injectable application

Heart rhythm changes are extremely uncommon but possible in people with underlying cardiac conditions