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doi:10.1001/jamanetworkopen.2024.21305

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GLP-1R agonists are important candidate for the treatment of NASH

For example, lower levels may be a factor in many health problems that are more common in older people

FOXO4-DRI has been investigated extensively in preclinical academic literature for p53 transactivation domain binding, senescence-associated apoptosis pathway research, p16 and IL-6 marker dynamics in senescent cell research models, and SASP (senescence-associated secretory phenotype) signaling