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doi: 10.3389/fphar.2025.1690036 Received 22 August 2025 Revised 26 October 2025 Accepted 31 October 2025 Published 17 November 2025 Volume 16 - 2025 Edited by Javier Echeverria, University of Santiago, Chile Reviewed by Rodrigo Castaneda, Korea Institute of Science and Technology (KIST), Republic of Korea Mengqi Zhou, Beijing University of Chinese Medicine, China Updates Copyright 2025 Zhao, Zhu, Zheng, Wang, Liu, Yu and Ma