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appropriate biologic screening of the serum and urine is required to detect and prevent terminal chronic kidney disease Identification of renal disease in suspected pSS should prompt an investigation to exclude other inflammatory disorders, such as lupus erythematosus, hepatitis C virus infection and IgG4-associated disorders Abstract Primary Sjgren syndrome (pSS) is an autoimmune disorder characterized by lymphoplasmacytic infiltration of the exocrine (salivary and lachrymal) glands that results in sicca symptoms (dryness of the eyes and mouth)

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