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AMPK is a critical bioenergy sensor, and the functional role of AMPK has been extensively studied in lipid metabolism (fatty acids, mitochondria, and cholesterol), glucose metabolism, protein synthesis, inflammation mitigation, mitochondrial biogenesis, apoptosis, and many other aspects [21]
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2) reduce the dose of oral minoxidil to 1.25 mg or 1.875 mg and add spironolactone 50-100 mg once daily if there are no contraindications and the patient accepts the potential side effects
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