The Bottom Line on Dual Therapy Taking Wegovy and phentermine at the same time is a clinical decision that must be made by a doctor
Under the condition of blocking GABAergic neurotransmission, light stimulation of PPG neurons results in an increase in the excitation of MCs suggesting the involvement of PPG neurons in shaping the MC firing patterns (Thiebaud et al., 2019)
Plan on at least a few weeks of inactivity, swelling, pain management, compression garments, and follow-ups
The retatrutide reconstitution chart provides volume-to-concentration tables that eliminate guesswork
General guidelines and dosing for patients with T2D: Initiate pramlintide at the 60 mcg dose taken immediately prior to major meals Titrate pramlintide to 120 mcg dose after 3 or more days with no clinically significant nausea Optimize insulin to achieve glycemic targets once the maintenance dose of pramlintide is reached and blood glucose concentrations are stable Practical Tips for Patients On Pramlintide Start With a Low Dose and Titrate Slowly Pramlintide can cause nausea, anorexia and vomiting, especially in T1D where a more gradual titration is required