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Much of what we know comes from animal studies

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Primarily from soy and soy products, isoflavones have been shown to improve arterial stiffness, TC, TG, LDL-C, HDL-C, fasting glucose, glucose homeostasis and HOMA-IR (Reference Glisic, Kastrati and Gonzalez-Jaramillo45Reference Tokede, Onabanjo and Yansane47)