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Though early work from companies like Vertex (Semma Tx acquisition) are focused on regeneration of pancreatic islets (for diabetes), Novo Nordisk recently inked a deal (including $75M upfront) with early-stage cell therapy player Aspect Biosystems

Microdosing protocols and vial economy Microdosing tirzepatide at sub-standard doses (0.5 mg to 2 mg weekly) stretches vial contents further but creates a significant tension with the stability window

There are still lots of unknowns about B12

Hypokalemia may lead to arrhythmias or muscle weakness, while hyperkalemia can cause cardiac arrest

Taking birth control, antacids, or chronic medications that interfere with absorption