TLDR: "Discontinuation of GLP-1RA treatment leads to weight regain, regardless of lifestyle interventions, and should therefore be considered a chronic therapy to prevent weight regain and associated undesirable outcomes related to obesity." Key findings: After stopping liraglutide, patients regained ~2.2 kg After stopping semaglutide/tirzepatide, patients regained ~9.7 kg Weight regain was proportional to initial weight loss Lifestyle changes alone DID NOT prevent regain Implication: GLP-1 receptor agonists are not a short-term solution
Medi-Cal nominal
Alarmingly, these websites lack instructions for use, including reconstituting the powder, drawing up an accurate, appropriate dose, and safe injection
For skin brightening, a course of weekly sessions is usually recommended, followed by maintenance drips every few weeks
It is critical that employers, health plans, and providers provide people with a solution that includes support for behavior change and mental health needs either complementary to the drug or instead of it