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The most useful records are the product label, batch-specific COA, HPLC purity documentation, LC-MS identity support, lot traceability, storage notes, and supplier documentation

Nevertheless, until long-term human data accumulates, the precautionary approach remains appropriate

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New England Journal of Medicine (2025) The REDEFINE 1 Phase 3 trial was a landmark 68-week, double-blind, randomized study comparing CagriSema (cagrilintide 2.4 mg plus semaglutide 2.4 mg) with semaglutide alone, cagrilintide alone, and placebo in 3,417 adults with obesity or overweight without diabetes