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GSH is an antioxidant which means that it helps prevent cell damage by detoxifying harmful substances in the body

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Notably, p38 MAPK is highly sensitive to oxidative signals, with low-dose H 2 O 2 sufficient to induce its rapid activation in muscle cells, preceding activation of catabolic regulators like FoxO and NF-B ( Once activated, p38 MAPK and JNK promote transcription of muscle atrophy-related genes