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Dondero K, et al

Mechanistically, SGLT2 inhibitors act predominantly through hemodynamic and cardiorenal pathways, whereas GLP-1 receptor agonists exert metabolic, anti-inflammatory, and anti-atherosclerotic effects, providing a rationale for potential complementarity

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Concomitant medicines : Clinicians should review all concurrent medications, particularly insulin or sulfonylureas, given the potential for hypoglycaemia with incretin-based agents